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Screening and Profiling Services

High-Throughput Screening and Profiling - Dose-Response Studies - Available Assays - Microfluidic Technology

Our comprehensive platform of kinaseproteasephosphatase, and epigenetic assays utilizes cutting-edge microfluidics and informatics tools to provide accurate and rapid results for your drug discovery program. Over 100 HTS projects have been completed in Nanosyn's state-of-the-art research facility.  We have the ability and capacity to quickly screen small compound sets or large libraries providing:

  • High precision and accuracy to ensure rapid selection of your best compounds and chemical series
  • Quick turnaround allows immediate SAR mining
  • Strict quality standards; statistical evaluation of all datasets
  • Low level of false positive and false negative values
  • Unique, proprietary informatics tools to analyze and visualize compound activity
  • Data reporting customized to your needs
  • Cradle to grave compound tracking
  • Flexibility for you to provide compounds in a variety of different formats
  • Options for compound screening:
    • All or part of your library
    • Nanosyn's unique compound library (i.e. 130K HPLC purified compound library)
    • A newly designed and synthesized library by Nanosyn to meet your needs
    • A third party library

Data visualization of high-throughput screen demonstrating activity (yellow) ranging from high to low selectivity for the enzyme target.

For more information about our Screening and Profiling services please contact us.

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