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Nanosyn Granted U.S. Patents for Chemical Library Synthesis Methods

Menlo Park, California, October 4, 2004

Nanosyn, Inc. today announced that the U.S. Patent & Trademark Office has issued two patents related to the company's technology. U.S. Patent No. 6,625,546 was issued on September 23, 2003 and claims methods for the direct identification of a chemical compound structure following solid phase synthesis of a chemical compound library. The second patent, U.S. Patent No. 6,625,546 was issued on September 28, 2004 and claims methods for using structural identification technology to increase the productivity of solid phase synthesis strategies. The patents also claim computerized implementations of the methods, including related software systems, databases, configurations of robotic and analytical laboratory instrumentation, and kits developed to enable licensees to carry out the methods in their own laboratories.

The methods claimed by both patents are components of Nanosyn's ANSTTM (Accelerated Nanosyn Synthesis Technology) platform, which enables Nanosyn to translate their clients' drug discovery hypotheses into focused libraries of drug-like molecules.

"Nanosyn is continuing to develop a patent estate designed to safeguard the value of our technology leadership position in nanoscale synthesis," said Olga Issakova, vice president of Nanosyn. "The intellectual property protection afforded by these new patents enables us to continue to invest in the development of technologies that help our clients make more efficient use of their drug development budgets and timelines."

About Nanosyn
Nanosyn, Inc. is a medicinal chemistry based organization providing made-to-order focused compound libraries, hit-to-lead optimization, and medicinal chemistry services. Nanosyn's "Chemistry on Demand" capabilities enable customers to apply the power of new screening technologies without making frustrating trade-offs between budgets, schedules, and research opportunities. The company's proprietary ANSTTM technology builds the best organic synthesis methods available into strategic configurations of instrumentation, software, and reagents, and uses real-time analytical data to orchestrate organic synthesis events. Founded in 1998, Nanosyn is privately held and self-funding. The company is based in Menlo Park, California. For additional information, please visit http://www.nanosyn.com.

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